Recombinant Protein or Antibody Production

Recombinant Protein or Antibody Production

Profacgen can offer you a full development package from proof of concept through to cGMP scale up in mammalian or microbial systems to produce recombinant proteins and biopharmaceutical antibodies.

For recombinant proteins

We provide technical capabilities to help our clients to accelerate their drug development process and make breakthrough discovery in a rapid and cost effective fashion. Our staff has decades of experience in the expression of recombinant proteins for Western pharmaceutical research organizations or companies.


 Mammalian or bacterial systems.

 Protein expression and purification, up to grams level.

 Process optimization and formulation development.

 Solubility enhancing techniques and specialized range of unique refolding techniques.

 High level of purity and endotoxin removal.

 Protein stability study and characterization.

For pharmaceutical antibodies

We offer integrated type of services for antibody production in antibody engineering, monoclonal production and cGMP scale up manufacturing.

We are experienced in providing our clients with services including antibody sequencing; scFv/Fab production and humanization for antibody engineering. Sequencing is quite important for patent issues and therapeutic approval; we have developed technologies to convert full monoclonal antibodies from a hybridoma cell line into single chain antibody fragments, which can be expressed in E. coli or CHO cells; humanized antibodies can reduce the human anti-murine antibody response (HAMA) and have a greater half-life in vivo.


 Antibody engineering and humanization.

 Immunization, hybridoma fusion and screening for monoclonal antibodies.

 Large scale production in milligram quantities or larger bulk amount.

 cGMP scale up production.


  •   Email:
  •   Tel: 1-631-448-8149
  •   Fax: 1-631-938-8127
  •   45-1 Ramsey Road, Shirley, NY 11967, USA