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CONTACT US

Tel: 1-631-448-8149
Fax: 1-631-938-8127

PEGylation Services

PEGylation is the process of attaching polyethylene glycol (PEG) polymer chains to target molecules to monitor their physiochemical properties. Various PEG moieties have been developed for different purposes.

Features

  Highly site-specific modifications.
  Improved target solubility and stability.
  Reduced immunogenicity and toxicity.
  Enhanced protection from proteolytic degradation.
  Increased in vivo efficacy and clinical effectiveness.
PEGylation Services

Polyethylene glycol, which is often abbreviated to PEG, is a chemical compound composed of repeated ethylene glycol units. PEG possesses several chemical properties that facilitate target protein's fuctions in diverse biological and pharmaceutical applications.

PEGylated proteins show great advantage over non-PEGylated proteins in terms of non-toxicity, low immunogenicity, high solubility and mobility in solution. PEGylation was also found to be able to mask the target protein drugs from the host’s immune system. The established therapeutic value and high flexibility of PEGylation made it a valuable tool in efficient drug development.

Profacgen has developed a series of technologies to increase the site-specificity of our PEGylation process. You can choose from the following according to your specific requirements or we can help recommend the best procedure for you!

PEGylation Services

CONTACT US
Email: info@profacgen.com
Tel: 1-631-448-8149
Fax: 1-631-938-8127
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA