Profacgen is a state-of-the-art protein service provider located in Long Island, NY, USA. We provide custom protein services in the biological sciences, enabling access to the latest tools, techniques, and expertise with competitive pricing and rapid turnaround time. We serve a broad spectrum of industrial and academic clients with a commitment to delivering high-quality data and customer services.
Protein expression and purification is where we started our business. We have unparalleled capacity in delivering custom proteins for both research needs and industrial scale.
We provide a wide range of expression systems from procaryotic cells to eukaryotic cells to cell free and animal free systems, from transient expression to stable expression. We produce recombinant proteins according to our customer specifications or by developing customized protocols in house.
We also provide bioprocess scale-up services. Our fermentation laboratories are equipped with advanced bioreactors that enable us to produce protein at large scale. Our customers can choose to enter the protein expression pipeline at any stage.
Profacgen is also equipped with a professional team focusing on protein interaction analysis. We have acquired extensive experience and expert knowledge in protein interaction assays. We provide a comprehensive list of assays from initial screening (Y2H screening; Pull-down couple with MS analysis) to interaction validation (Co-IP, FRET etc.) to affinity and binding kinetics study (SPR analysis).
We offer high-throughput screening services including enzyme substrate screening, GPCR screening, Transporter screening and Ion channel screening. We have developed specific assays for each of the above classes of molecules for accurate and high throughput study. We offer a large compound library and various cell models. Our screening service allows identification of specific substrates, activators, inhibitors agonists, antagonists or modulators.
We have also developed a series of protein engineering techniques including protein labeling by fluorescent dye, stable isotope, PEG, biotin etc. to meet the research requirements of our customers.