Background
This gene encodes a glycoprotein with deamidase, esterase and carboxypeptidase activities. The encoded protein associates with and provides a protective function to the lysosomal enzymes beta-galactosidase and neuraminidase. Deficiency of the related gene in humans results in galactosialidosis. The proprotein is processed into two shorter chains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
References
Seyrantepe V., et al. (2008) Circulation. 117:1973-1981.
Hiraiwa M., et al. (1999) Cell Mol Life Sci. 56:894-907.