The three-dimensional structure of a protein provides essential information about its biological function and facilitates the design of therapeutic drugs that specifically bind to the protein target. Recent years have witnessed a tremendous increase in the number of experimentally determined protein structures. It is, however, still generally tedious and time-consuming to solve protein structures with experimental approaches. Therefore, computational approaches represent an alternative and supplement to experimental methods to obtain three-dimensional structure of a protein.
Profacgen takes advantage of computational modeling methods to predict the three-dimensional structure of proteins of your interest. We have extensive experiences with the modeling of various kinds of proteins. The resultant structural models are all quality validated and can be used for a variety of purposes, such as annotation of genes with unknown function and structure-based drug design. The structure modeling procedure also works seamlessly with downstream computational modeling protocols including docking and molecular dynamics simulation.
Please see below the types of modeling we can do for you:
Please feel free to contact us with your protein structure determination projects. Profacgen is here to offer you professional and thoughtful service.