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Discovery & Early Development

Discovery & Early Development

Profacgen's Drug Discovery Platform focuses on transforming original scientific concepts into lead compounds with defined structures, clear mechanisms, and genuine development potential. We don't just deliver the ten core technical modules listed above—through deep integration and customized design, we ensure data from every step directly serves your program's decision-making.

Core Service Modules: A Detailed Look

From Hypothesis to Validated Target: A Stronger Biological Starting Point

Our Target Identification and Validation services go beyond simple literature reviews. By integrating multi-omics data mining through our Bioinformatics Platform with Experiment Consulting and Design, we construct a complete evidence chain—from sequence analysis and structure prediction to functional biology hypotheses—ensuring every drop of reagent is invested in scientifically grounded targets.

Protein Engineering: Tailoring Molecular Tools to Your Exact Needs

Whether it's Protein Labeling services (fluorescent, isotopic, biotin, etc.) to support interaction studies, or customized Protein Mutant Library Construction (site-directed, random, or saturation mutagenesis), we deliver more than just protein samples—we provide high-quality tool molecules ready for screening, with activity and purity rigorously QC-tested.

Screening and Functional Assessment: Data Quality Determines Candidate Success

Our Functional & Binding Assays cover enzymology, kinetics, affinity, and more, while our Screening and Profiling Services support high-throughput screening (HTS) from 96-well to 1536-well formats, with scalable analyses for dose-response, selectivity, and off-target effects. Data directly outputs SAR (Structure-Activity Relationship) insights—no secondary processing required.

Chemistry Optimization and Frontier Therapies: Beyond Traditional Screening Boundaries

The Lead Discovery Chemistry team supports hit-to-lead optimization with building block synthesis, scaffold hopping, and more. For undruggable targets, our Targeted Protein Degradation services provide end-to-end capability—from ligand discovery and linker design to ternary complex validation—helping you explore novel modalities like protein degrader and molecular glues.

Why Our Discovery Services Are Built for Translation

Our Commitment: Driving Decisions with Scientific Evidence

We don't produce compound libraries—we produce actionable data. We don't promise pipelines—we deliver optimizable starting points.

Contact Us

Call for specific technical proposals or apply for a free technical fit consultation. Our expert team will respond within 24 hours to co-design the optimal experimental path from target to lead molecule.

Online Inquiry

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