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Corynebacterium glutamicum Expression Systems

Corynebacterium glutamicum Expression Systems

Corynebacterium glutamicum (C.glutamicum) is a highly promising alternative prokaryotic host for recombinant protein expression, and has been developed as a currently leading bacterial protein expression system. As it possesses several significant features over conventional bacterial expression system as follow.

Corynebacterium glutamicum Expression Systems
Corynebacterium glutamicum, a soil-derived Gram-positive actinobacterium, has been widely used for the productions of biochemical molecules such as amino acids, nucleic acids, alcohols, and organic acids.


  •  Fast-growing
  •  Low cost of cultivation
  •  Large-scale protein expression
  •  Easy genetic manipulation
  •  Non-pathogenic
  •  Endotoxin free production
  •  Minimal protease activities
  •  Minimizing the purification steps
  •  Secreting properly folded and functional protein to the culture

To date, C.glutamicum has been generally recognized as a safe host for the industrial production of biologics (such as antibodies, growth factors, and hormones), biochemicals (such as L-glutamate and L-lysine) and enzymes. Various types of plasmid vectors, as well as methods of protein secretion and purification against this expression system have been developed and optimized, providing powerful support for both industrial and pharmaceutical purposes. Some successful cases of actual application also have proven unparalleled potential of this expression system.

Profacgen provides you with one ultimate solution of C.glutamicum production. Our service can be tailored according to your specialized requirements. Our expertise guarantees high protein quality, short turnaround time, and the best price in the market!

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