Service Search Product Search Gene Search
HOME

Recombinant Cynomolgus PDCD1 Protein(His tag) (CH0055PL)

Recombinant Cynomolgus PDCD1 Protein (B0LAJ3) (Leu 25 - Gln 167) with a polyhistidine tag at the C-terminus was expressed in HEK293.
Size
Price
Qty
Order
Size:50ug
Price:$990.00
Qty:
Order: Order Online
Bulk Inquiry
PRODUCT INFORMATION
Cat.No.
CH0055PL
Synonyms
Programmed cell death 1; PDCD1
Species
Cynomolgus
Accession
Source
HEK293
Tag
His
Predicted N Terminal
Leu 25
Form
Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Bio-activity
Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus PD-1, His Tag at 5μg/mL (100 ul/well),can bind Cynomolgus PD-L1, Fc Tag with a linear of 0.1-2 μg/mL.
Molecular Mass
Recombinant Cynomolgus PDCD1 Protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 16.8 kDa. DTT-reduced Protein migrates as 26-45 kDa in SDS-PAGE due to different glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 95 % by SDS-PAGE.

Usage Guide
Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Dissolve with double distilled water.
Warning
For research use only!

BACKGROUND
Background
Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

Send Inquiry Now!
Name:
*Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "Profacgen" as verification code.
CONTACT US
Tel: 1-631-448-8149
Fax: 1-631-938-8127
CONTACT US
Email: info@profacgen.com
Tel: 1-631-448-8149
Fax: 1-631-938-8127
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA