Recombinant Cynomolgus PVRL2 Protein(His tag)

Recombinant Cynomolgus PVRL2 Protein(His tag) (CH0274PL)

Recombinant Cynomolgus PVRL2 Protein (Q0MSE5) (Met1-Leu360) with a polyhistidine tag at the C-terminus was expressed in HEK293.

Size Price Qty
50ug $390.00

PRODUCT INFORMATION

Cat.No.
CH0274PL
Synonyms
PVRL2; Nectin-2; CD112
Species
Cynomolgus
Accession
Source
HEK293
Tag
His
Predicted N Terminal
Gln 32
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Molecular Mass
Recombinant Cynomolgus PVRL2 consists 340 amino acids and predicts a molecular mass of 37.2 kDa.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 90 % by SDS-PAGE.

Usage Guide

Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.
Warning
For research use only!

BACKGROUND

Background
Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT.

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