Recombinant Mouse Ctla4 Protein(hIgG-His tag) (MI0014CS)

Cat.No.

MI0014CS

Synonyms

CTLA4; CD152 antigen; Cd152; Ly-56; Ctla-4;

Form

Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

Molecular Mass

40.6kDa (363aa)
40-57KDa (SDS-PAGE under reducing conditions.)

AA Sequence

IQVTQPSVVL ASSHGVASFP CEYSPSHNTD EVRVTVLRQT NDQMTEVCAT TFTEKNTVGF LDYPFCSGTF NESRVNLTIQ GLRAVDTGLY LCKVELMYPP PYFVGMGNGT QIYVIDPEPC PDSDLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH
HHH

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Purity

> 90% by SDS - PAGE

Storage

Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.

Concentration

0.5mg/ml (determined by Absorbance at 280nm)

Warning

For research use only!

Background

This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References

Krummey SM., et al. (2014) J. Immunol. 192:2495-2504.
Jain N., et al. (2013) Nat. Med. 19:1632-1637.
Yu CR., et al. (2013) J. Immunol. 191:5036-5043.

Tag

hIgG-His tag

Species

Mouse

Source

Insect cells

Background

This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References

Krummey SM., et al. (2014) J. Immunol. 192:2495-2504.
Jain N., et al. (2013) Nat. Med. 19:1632-1637.
Yu CR., et al. (2013) J. Immunol. 191:5036-5043.