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Recombinant Human ASGR2 Protein(His tag) (HH0215AL)

Recombinant Human ASGR2 Protein (P07307) (Gln80-Ala311) with an N-terminal polyhistidine tag was expressed in HEK293.

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10ug $471.90
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PRODUCT INFORMATION

Cat.No.
HH0215AL
Synonyms
ASGR2; CLEC4H2; HL-2; HBXBP; ASGPR2; ASGP-R2
Species
Human
Accession
Source
HEK293
Tag
His
Predicted N Terminal
His
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Molecular Mass
Recombinant Human ASGR2 comprises 252 amino acids and has a predicted molecular mass of 28.9 kDa. The apparent molecular mass of the protein is approximately 37-42 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 95 % by SDS-PAGE.

BACKGROUND

Background
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

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