Lyophilized from sterile 20mM PB, pH 7.4, 150mM NaCl.
Bio-activity
The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.
Molecular Mass
Recombinant Human CCL17 Protein is a single non-glycosylated polypeptide chain and has a molecular mass of approximately 8.1 kDa.
AA Sequence
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 97 % by SDS-PAGE.
BACKGROUND
Background
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
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