Recombinant Human CD33 Protein(His tag)

Recombinant Human CD33 Protein(His tag) (HH0205CL)

Recombinant Human CD33 Protein (P20138) (Met1-His259) with a C-terminal polyhistidine tag was expressed in HEK293.

Size Price Qty
50ug $390.00

PRODUCT INFORMATION

Cat.No.
HH0205CL
Synonyms
CD33; p67; SIGLEC 3; SIGLEC3; gp67; SIGLEC-3
Species
Human
Accession
Source
HEK293
Tag
His
Predicted N Terminal
Asp 18
Form
Lyophilized from sterile PBS, pH 7.4, 10% glycerol, 5 % trehalose and 5 % mannitol.
Molecular Mass
Recombinant Human CD33 comprises 253 amino acids and has a predicted molecular mass of 28.2 kDa. The apparent molecular mass of the protein is approximately 40-46 kDa in SDS-PAGE under reducing conditions.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 90 % by SDS-PAGE.

Usage Guide

Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.
Warning
For research use only!

BACKGROUND

Background
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

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