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Recombinant Human CD4 Protein(His tag) (HH0051CL)

Recombinant Human CD4 Protein (P01730) (Lys 26 - Trp 390) with a polyhistidine tag at the C-terminus was expressed in HEK293.

Datasheet

Size Price Qty
100ug $869.00
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PRODUCT INFORMATION

Cat.No.
HH0051CL
Synonyms
CD4; CD4 receptor; CD4 antigen (p55);
Accession
CD4
Predicted N Terminal
Lys 26
Form
Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Molecular Mass
Recombinant Human CD4 Protein is fused with polyhistidine tag at the C-terminus, and has a calculated MW of 41.5 kDa. DTT-reduced Protein migrates as 50 kDa in SDS-PAGE due to glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 92 % by SDS-PAGE.
Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Dissolve with double distilled water.
Warning
For research use only!
Background
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1 (PubMed:2214026, PubMed:16331979, PubMed:9641677). Down-regulated by HIV-1 Vpu (PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed:7909607).
Tag
His
Species
Human
Source
HEK293

BACKGROUND

Background
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1 (PubMed:2214026, PubMed:16331979, PubMed:9641677). Down-regulated by HIV-1 Vpu (PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed:7909607).
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