Recombinant Human CD79B Protein(Fc tag) (HH0035CL)

Cat.No.

HH0035CL

Synonyms

CD79B; B29; Ig-beta; IGB; AGM6;

Accession

CD79B

Predicted N Terminal

Ala 29

Form

Lyophilized from sterile 50 mM tris, 100 mM glycine, pH7.5, 10% Trehalose.

Molecular Mass

Recombinant Human CD79B Protein is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 41.8 kDa. The reducing protein migrates as 50-65 kDa in SDS-PAGE due to glycosylation.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 92 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Dissolve with double distilled water.

Warning

For research use only!

Background

Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Tag

Fc

Species

Human

Source

HEK293

Background

Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.