Recombinant Human CD86 Protein(His tag) (HH0141CL)

Recombinant Human CD86 Protein (P42081) (Met 1-His 239) with a polyhistidine tag at the C-terminus was expressed in HEK293.

Datasheet

Size	Price	Qty
100ug	$429.00

Order Online Bulk Inquiry

PRODUCT INFORMATION

Cat.No.

HH0141CL

Synonyms

CD86; B7 2; B7.2; BU63; FUN-1; B70; B7-2; LAB72; CD28LG2;

Species

Human

Accession

CD86

Source

HEK293

Tag

His

Predicted N Terminal

Leu 20

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its binding ability in a functional ELISA . Immobilized human CD86 at 20 μg/ml (100 μl/well) can bind human CD28 with a linear ranger of 32-800 ng/ml.

Molecular Mass

Recombinant Human B7-2 consists of 228 amino acids and has a predicted molecular mass of 26.2 kDa. In SDS-PAGE, the apparent molecular mass of rhB7-2 is approximately 55-60 kDa due to glycosylation.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 97 % by SDS-PAGE.

BACKGROUND

Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).

Online Inquiry

Fill out this form and one of our experts will respond to you within one business day.