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Recombinant Human CDH1 Protein(Fc tag) (HH0102CL)

Recombinant Human CDH1 Protein (P12830) (Met1-Ile707) with the Fc region of human IgG1 at the C-terminus was expressed in HEK293.

Size Price Qty
50ug $396.00
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PRODUCT INFORMATION

Cat.No.
HH0102CL
Synonyms
CDH1; UVO; cadherin-1; CD324; E Cadherin; E-Cadherin; CDHE; ECAD; LCAM; Arc-1;
Species
Human
Accession
Source
HEK293
Tag
Fc
Predicted N Terminal
Gln 23 & Asp 155
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Bio-activity
Measured by the ability of the immobilized protein to support the adhesion of MCF-7 human breast adenocarcinoma cells.
When cells are added to E-Cad coated plates (5 μg/mL, 100 μL/well), approximately 33% will adhere specifically after 90 minutes at 37 ?C
Molecular Mass
Recombinant Human E-Cad/Fc is a disulfide-linked homodimer. The reduced monomer comprises 791 amino acids and has a predicted molecular mass of 87.1 kDa. The apparent molecular mass of the protein is approximately 116-126 kDa in SDS-PAGE under reducing conditions.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 90 % by SDS-PAGE.

BACKGROUND

Background
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
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