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Recombinant Human CFH Protein(His tag) (HH0144CL)

Recombinant Human CFH Protein (P08603) (Ser 860-Arg 1231) with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus was expressed in HEK293.

Size Price Qty
50ug $396.00
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PRODUCT INFORMATION

Cat.No.
HH0144CL
Synonyms
CFH; ARMS1; beta 1H; FHL1; HUS; beta-1H; factor H; FH; HF; HF1; HF2; AHUS1; AMBP1; ARMD4; CFHL3;
Species
Human
Accession
CFH
Source
HEK293
Tag
His
Predicted N Terminal
Ser 860
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Bio-activity
Measured by its ability to bind biotinylated human DMP1 in a functional ELISA.
Molecular Mass
Recombinant Human CFH consists of 383 amino acids and has a calculated molecular mass of 43 kDa. The apparent molecular mass of rh CFH is approximately 55-60 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 97 % by SDS-PAGE.

BACKGROUND

Background
Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.
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