F8; coagulation factor VIII; DXS1253E; Factor VIIIF8B; FVIII; HEMA; hemophilia A; factor VIII F8B
Each 250IU of lyophilized protein contain 6mg/vial L-histidine, 72mg/vial NaCl, 1mg/vial CaCl22H2O, 0.4mg/vial Tween 80, 12mg/vial Sucrose, pH 7.0 (After reconstitution with 4ml of 0.9% Saline).
The specific activity was found to be 10,169 IU/mg.
Antihemophilic Facor Human Recombinant produced in CHO is a glycosylated polypeptide chain having a total amino acids of 1438 (170kd) and consisting of two dimer chains 80 kD and 90 kD.
Greater than 97.0% as determined by SDS-PAGE.
Lyophilized Factor-VIII although stable at room temperature for 3 weeks, should be stored desiccated below -18 centigrade. Upon reconstitution Factor-VIII should be stored at 4 centigrade between 2-7 days and for future use below -18 centigrade.
Please prevent freeze-thaw cycles.
It is recommended to reconstitute 250IU lyophilized Factor-VIII in 4ml of 0.9% Saline, After reconstitution, Factor-VIII concentration will be 60IU/ml and should be used within 3 hours.
For research use only!