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Recombinant Human FOLH1 Protein(His tag) (HH0219FL)

Recombinant Human FOLH1 Protein (Q04609) (Lys44-Ala750) with a polyhistidine tag at the N-terminus was expressed in HEK293.

Size Price Qty
10ug $319.00
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PRODUCT INFORMATION

Cat.No.
HH0219FL
Synonyms
FOLH1; FOLH; GCP2; GCPII; NAALAD1; NAALAdase; PSM; PSMA; NAALADase I; FGCP; mGCP
Species
Human
Accession
Source
HEK293
Tag
His
Predicted N Terminal
His
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Molecular Mass
Recombinant Human FOLH1 consists 725 amino acids and predicts a molecular mass of 81.7 kDa.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 95 % by SDS-PAGE.

BACKGROUND

Background
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
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