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Recombinant Human GZMB Protein(His tag) (HH0114GL)

Recombinant Human GZMB Protein (P10144) (Met 1-Tyr 247) with a C-terminal polyhistidine tag was expressed in HEK293.

Size Price Qty
10ug $319.00
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PRODUCT INFORMATION

Cat.No.
HH0114GL
Synonyms
GZMB; CCPI; CGL 1; CGL1; CSP B; CTSGL1; HLP; SECT; C11; CTLA-1; CSPB; CGL-1; CSP-B; CTLA1;
Species
Human
Accession
Source
HEK293
Tag
His
Predicted N Terminal
Gly 19
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Molecular Mass
Recombinant Human Granzyme B consists of 240 amino acids and has a calculated molecular mass of 27 kDa. As a result of glycosylation, the apparent molecular mass of rhGranzyme B is approximately 36 kDa in SDS-PAGE under reducing conditions.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 97 % by SDS-PAGE.

BACKGROUND

Background
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
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