Recombinant Human IL13 Protein (HE0004IL)

Recombinant Human IL13 Protein (P35225) (112 amino acids) with no tag was expressed in E.coli.

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10ug	$319.00

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PRODUCT INFORMATION

Cat.No.

HE0004IL

Synonyms

IL13; interleukin-13; ALRH; BHR1; IL 13; IL-13;

Species

Human

Accession

IL13

Source

E. coli

Form

Lyophilized from sterile PBS, pH 7.4 with 5 % trehalose.

Bio-activity

The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1 ng/ml, corresponding to a specific activity of> 1.0 × 10^6 IU/mg.

Molecular Mass

Recombinant Human IL13 Protein is a single non-glycosylated polypeptide chain and has a molecular mass of approximately 12.5 kDa.

AA Sequence

GPVPPSTALR ELIEELVNIT QNQKAPLCNG SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL HLKKLFREGR FN

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 97 % by SDS-PAGE.

BACKGROUND

Background

Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages (By similarity).

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