Recombinant Human IL17A Protein (HE0198IL)

Recombinant Human IL17A Protein (Q16552) (Ile20-Ala155) with a N-terminal Met was expressed in E. coli.

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20ug	$319.00

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PRODUCT INFORMATION

Cat.No.

HE0198IL

Synonyms

IL17A; interleukin-17A; IL 17; IL 17A; CTLA-8; IL17; CTLA8; IL-17; IL-17A

Species

Human

Accession

IL17A

Source

E. coli

Predicted N Terminal

Met

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.

Bio-activity

Measured by its ability to induce IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 15-75 ng/mL.

Molecular Mass

Recombinant Human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa. It migRates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 97 % by SDS-PAGE.

BACKGROUND

Background

Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).

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