Recombinant Human PDGFB Protein (HE0067PL)

Cat.No.

HE0067PL

Synonyms

PDGFB; SSV; PDGF-2; PDGF subunit B; SIS; PDGF2; c-sis;

Accession

PDGFB

Form

Liquid in PBS Buffer.

Molecular Mass

Recombinant Human PDGFB Protein is a disulfide-linked homodimer of two B chains (218 total amino acids) and has a molecular mass of approximately 27 kDa.

Endotoxin

< 0.01 EU per 1 microgram of protein (determined by LAL method).

Purity

> 95 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Warning

For research use only!

Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).

Species

Human

Source

E. coli

Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).