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Recombinant Human PDGFB Protein (HE0067PL)

Recombinant Human PDGFB Protein (P01127) (two B chains 218 amino acids) with no tag was expressed in E. coli.

Size Price Qty
100ug $649.00
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PRODUCT INFORMATION

Cat.No.
HE0067PL
Synonyms
PDGFB; SSV; PDGF-2; PDGF subunit B; SIS; PDGF2; c-sis;
Species
Human
Accession
Source
E. coli
Form
Liquid in PBS Buffer.
Molecular Mass
Recombinant Human PDGFB Protein is a disulfide-linked homodimer of two B chains (218 total amino acids) and has a molecular mass of approximately 27 kDa.
Endotoxin
< 0.01 EU per 1 microgram of protein (determined by LAL method).
Purity
> 95 % by SDS-PAGE.

BACKGROUND

Background
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
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