Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Molecular Mass
Recombinant Human PIGR Protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 68.7 kDa. DTT-reduced Protein migrates as 85-95 kDa in SDS-PAGE due to glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 98 % by SDS-PAGE.
BACKGROUND
Background
This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
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