Recombinant Human ROR2 Protein(Fc tag) (HH0057RL)

Cat.No.

HH0057RL

Synonyms

ROR2; BDB; BDB1; NTRKR2;

Accession

ROR2

Predicted N Terminal

Val 34

Form

Lyophilized from sterile 50 mM tris, 100 mM glycine, pH7.5, 10% Trehalose.

Molecular Mass

Recombinant Human ROR2 Protein is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 68 kDa. DTT-reduced Protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 95 % by SDS-PAGE.

Storage

In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.

Reconstitution

Dissolve with double distilled water.

Warning

For research use only!

Background

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).

Tag

Fc

Species

Human

Source

HEK293

Background

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).