Recombinant Human ROR2 Protein(Fc tag) (HH0057RL)

Recombinant Human ROR2 Protein (Q01974) (Val 34 - Gly 403) with a human IgG1 Fc tag at the C-terminus was expressed in HEK293.

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50ug	$759.00

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PRODUCT INFORMATION

Cat.No.

HH0057RL

Synonyms

ROR2; BDB; BDB1; NTRKR2;

Species

Human

Accession

ROR2

Source

HEK293

Tag

Predicted N Terminal

Val 34

Form

Lyophilized from sterile 50 mM tris, 100 mM glycine, pH7.5, 10% Trehalose.

Molecular Mass

Recombinant Human ROR2 Protein is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 68 kDa. DTT-reduced Protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation.

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 95 % by SDS-PAGE.

BACKGROUND

Background

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).

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