Recombinant Human SERPINI1 Protein (HE0021SL)

Recombinant Human SERPINI1 Protein (Q99574) (394 amino acids) with no tag was expressed in E.coli.

Size	Price	Qty
25ug	$319.00

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PRODUCT INFORMATION

Cat.No.

HE0021SL

Synonyms

SERPINI1; PI-12; serpin I1; PI12;

Species

Human

Accession

SERPINI1

Source

E. coli

Form

Lyophilized from sterile PBS, pH 7.4.

Bio-activity

The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.5 μg/ml, corresponding to a specific activity of> 2000 IU/mg.

Molecular Mass

Recombinant Human SERPINI1 Protein is a single non-glycosylated polypeptide chain and has a molecular mass of approximately 44.7 kDa.

AA Sequence

TGATFPEEAI ADLSVNMYNR LRATGEDENI LFSPLSIALA MGMMELGAQG STQKEIRHSM GYDSLKNGEE FSFLKEFSNM VTAKESQYVM KIANSLFVQN GFHVNEEFLQ MMKKYFNAAV NHVDFSQNVA VANYINKWVE NNTNNLVKDL VSPRDFDAAT YLALINAVYF KGNWKSQFRP ENTRTFSFTK DDESEVQIPM MYQQGEFYYG EFSDGSNEAG GIYQVLEIPY EG

Endotoxin

< 1.0 EU per 1 microgram of protein (determined by LAL method).

Purity

> 95 % by SDS-PAGE.

BACKGROUND

Background

Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.

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