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Recombinant Human TIMP2 Protein(His tag) (HH0060TL)

Recombinant Human TIMP2 Protein (P16035) (Cys 27 - Pro 220) with a polyhistidine tag at the C-terminus was expressed in HEK293.

Size Price Qty
50ug $649.00
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PRODUCT INFORMATION

Cat.No.
HH0060TL
Synonyms
TIMP2; CSC 21K; TIMP-2; CSC-21K;
Species
Human
Accession
Source
HEK293
Tag
His
Predicted N Terminal
Cys 27
Form
Lyophilized from sterile 50 mM Tris, 150 mM NaCl, 0.05% Brij-35, pH 7.5, 10% Trehalose.
Molecular Mass
Recombinant Human TIMP2 Protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 22.6 kDa. DTT-reduced Protein migrates as 22 kDa in SDS-PAGE.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 98 % by SDS-PAGE.

BACKGROUND

Background
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
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