Recombinant Human YWHAH Protein (HE0040YS)
Recombinant Human YWHAH Protein (NP_003396) (1-246aa) was expressed in E.coli.
| Size | Price | Qty |
|---|---|---|
| 100ug | $495.00 |
PRODUCT INFORMATION
Cat.No.
HE0040YS
Synonyms
YWHAH; YWHA1; 14-3-3 protein eta; 14 3 3 eta
Species
Human
Accession
Source
E. coli
Form
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass
28.2kDa (246aa)
AA Sequence
MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIEKELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
Purity
> 90% by SDS - PAGE
BACKGROUND
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.
References
Maksymowych WP., et al. (2014) Arthritis Res Ther. 16(2): R99.
Sato S., et al. (2002) J Biol Chem. 277: 39360-39367
Sato S., et al. (2002) J Biol Chem. 277: 39360-39367
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