Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Bio-activity
Measured by its ability to bind biotinylated Cynomolgus IL18 in functional ELISA.
Molecular Mass
Recombinant Mouse IL18BP comprises 176 amino acids and has a predicted molecular mass of 19.4 kDa. In SDS-PAGE under reducing conditions, rm IL18BP migRates between 35-50 kDa due to different glycosylation.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 95 % by SDS-PAGE.
BACKGROUND
Background
Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response (By similarity).
Online Inquiry
Fill out this form and one of our experts will respond to you within one business day.