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Recombinant Mouse Ces1g Protein (His tag) (MI0022CS)

Recombinant Mouse Ces1g Protein (NP_067431) (19-565aa) with C-terminus His tag was expressed in Insect cells.

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50ug $660.00
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PRODUCT INFORMATION

Cat.No.
MI0022CS
Synonyms
Liver carboxylesterase 1; CES1G; Ces-1; Ces1; Ses-1
Species
Mouse
Source
Insect cells
Tag
His tag
Form
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass
61.9kDa (556aa)
50-70KDa (SDS–PAGE under reducing conditions.)
AA Sequence
ADPHPSLPPV VHTVHGKVLG KYVTLEGFSQ PVAVFLGVPF AKPPLGSLRF APPEPAEPWS FVKHTTSYPP LCYQNPEAAL RLAELFTNQRKIIPHKFSED CLYLNIYTPA DLTQNSRLPV MVWIHGGGLV IDGASTYDGV PLAVHENVVV VVIQYRLGIW GFFSTEDEHS RGNWGHLDQVAALHWVQDNI ANFGGNPGSV TIFGESAGGE SVSVLVLSPL AKNLFHRAIA QSSVIFNPCL FGRAARPLAK KIAALAGCKT TTSAAMVHCLRQKTEDELLE VSLKMKFGTV DFLGDPRESY PFLPTVIDGV LLPKAPEEIL AEKSFNTVPY MVGINKHEFG WIIPMFLDFP LSERKLDQKT
AASILWQAYP ILNISEKLIP AAIEKYLGGT EDPATMTDLF LDLIGDIMFG VPSVIVSRSH RDAGAPTYMY EYQYRPSFVS DDRPQELLGDHADELFSVWG APFLKEGASE EEINLSKMVM KFWANFARNG NPNGEGLPHW PEYDQKEGYL QIGVPAQAAH RLKDKEVDFW TELRAKETAERSSHREHVEL HHHHHH
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity
> 90% by SDS - PAGE

BACKGROUND

Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with Ces7 and Ces3 on chromosome 8.
References
Satoh T., et al. (2006) Chem Biol Interact. 162:195-211.
Fleming CD., et al. (2007) Biochemistry. 46:5063-5071.
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