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Recombinant Mouse Ctsa Protein(hIgG-His tag) (MI0015CS)

Recombinant Mouse Ctsa Protein (NP_001033581) (24-474aa) with C-terminus His tag was expressed in Insect cells.

Size Price Qty
50ug $495.00
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PRODUCT INFORMATION

Cat.No.
MI0015CS
Synonyms
CTSA; cathepsin A; PPCA; Ppgb; AU019505;
Species
Mouse
Source
Insect cells
Tag
His tag
Form
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass
52.4kDa (459aa)
50-70kDa (SDS-PAGE under reducing conditions)
AA Sequence
APDQDEIDCL PGLAKQPSFR QYSGYLRASD SKHFHYWFVE SQNDPKNSPV VLWLNGGPGC SSLDGLLTEH GPFLIQPDGV TLEYNPYAWNLIANVLYIES PAGVGFSYSD DKMYVTNDTE VAENNYEALK DFFRLFPEYK DNKLFLTGES YAGIYIPTLA VLVMQDPSMN LQGLAVGNGLASYEQNDNSL VYFAYYHGLL GNRLWTSLQT HCCAQNKCNF YDNKDPECVN NLLEVSRIVG KSGLNIYNLY APCAGGVPGR HRYEDTLVVQDFGNIFTRLP LKRRFPEALM RSGDKVRLDP PCTNTTAPSN YLNNPYVRKA LHIPESLPRW DMCNFLVNLQ YRRLYQSMNS QYLKLLSSQK
YQILLYNGDV DMACNFMGDE WFVDSLNQKM EVQRRPWLVD YGESGEQVAG FVKECSHITF LTIKGAGHMV PTDKPRAAFT MFSRFLNKEPYVEHHHHHH
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity
> 90% by SDS - PAGE

BACKGROUND

Background
This gene encodes a glycoprotein with deamidase, esterase and carboxypeptidase activities. The encoded protein associates with and provides a protective function to the lysosomal enzymes beta-galactosidase and neuraminidase. Deficiency of the related gene in humans results in galactosialidosis. The proprotein is processed into two shorter chains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
References
Seyrantepe V., et al. (2008) Circulation. 117:1973-1981.
Hiraiwa M., et al. (1999) Cell Mol Life Sci. 56:894-907.
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