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Recombinant Mouse F3 Protein (hIgG-His tag) (MI0020FS)

Recombinant Mouse F3 Protein (NP_034301) (29-251aa) with C-terminus His tag was expressed in Insect cells.
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Size:50ug
Price:$450.00
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PRODUCT INFORMATION
Cat.No.
MI0020FS
Synonyms
F3; coagulation factor III; tissue factor; TF; Cf3; Cf-3; CD142; AA409063;
Species
Mouse
Source
Insect cells
Tag
His tag
Form
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass
26.4kDa (232aa)
28-40KDa (SDS–PAGE under reducing conditions.)
AA Sequence
ADPAGIPEKA FNLTWISTDF KTILEWQPKP TNYTYTVQIS DRSRNWKNKC FSTTDTECDL TDEIVKDVTW AYEAKVLSVP RRNSVHGDGDQLVIHGEEPP FTNAPKFLPY RDTNLGQPVI QQFEQDGRKL NVVVKDSLTL VRKNGTFLTL RQVFGKDLGY IITYRKGSST GKKTNITNTNEFSIDVEEGV SYCFFVQAMI FSRKTNQNSP GSSTVCTEQW KSFLGEHHHH HH
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity
> 95% by SDS - PAGE

Usage Guide
Storage
Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration
0.5mg/ml (determined by Absorbance at 280nm)
Warning
For research use only!

BACKGROUND
Background
This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis.
References
Versteeg HH., et al. (2003) Carcinogenesis. 24:1009-1013.
Morrissey JH., et al. (2004) Int J Hematol. 79:103-108.

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