Service Search Product Search Gene Search
HOME

Recombinant Sheep IFNT1 Protein (SE0014IL)

Recombinant Sheep IFNT1 Protein (P56828) (172 amino acids) with no tag was expressed in E.coli.
Size
Price
Qty
Order
Size:10ug
Price:$290.00
Qty:
Order: Order Online
Bulk Inquiry
PRODUCT INFORMATION
Cat.No.
SE0014IL
Synonyms
Interferon tau-1; IFNT1; IFN-tau-1; TP-1; Trophoblastin
Species
Sheep
Accession
Source
E. coli
Form
Lyophilized from sterile PBS, pH 7.4.
Bio-activity
The specific activity determined by a viral resistance assay is no less than 1.0 × 10^7 IU/mg.
Molecular Mass
Recombinant Sheep IFNT1 Protein is a single non-glycosylated polypeptide chain and has a molecular mass of approximately 19.9 kDa.
AA Sequence
CYLSRKLMLD ARENLKLLDR MNRLSPHSCL QDRKDFGLPQ EMVEGDQLQK DQAFPVLYEM LQQSFNLFYT EHSSAAWDTT LLEQLCTGLQ QQLDHLDTCR GQVMGEEDSE LGNMDPIVTV KKYFQGIYDY LQEKGYSDCA WEIVRVEMMR ALTVSTTLQK RLTKMGGDLN SP
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
> 97 % by SDS-PAGE.

Usage Guide
Storage
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). Avoid repeated freeze/thaw cycles.
Reconstitution
Dissolve with double distilled water.
Warning
For research use only!

BACKGROUND
Background
Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

Send Inquiry Now!
Name:
*Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "Profacgen" as verification code.
CONTACT US
Tel: 1-631-448-8149
Fax: 1-631-938-8127
CONTACT US
Email: info@profacgen.com
Tel: 1-631-448-8149
Fax: 1-631-938-8127
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA